Main
Alejandro M Carrasco
I am a bioinformatician and deep learning enthusiast with a strong background in biotechnology and genetics
Work experience
Education
PhD. in Bioinformatics
University College London
London, United Kingdom
2024 - 2021
- Thesis: Using genomics to understand Parkinson’s disease progression
- Developed and applied multiple pipelines to understand the biological impact of variants nominated in genetic studies
MSc in Bioinformatics
University of Murcia
Murcia, Spain
2020 - 2019
- Thesis: Use of community detection algorithms to create co-expression and co-occurrence networks
- Tested the proposed pipeline over transcriptomics and genomics data sets from AMP-PD project
BSc in Biotechnology
University of Murcia
Murcia, Spain
2018 - 2014
- Thesis: Review on the key role of inflammation in diabetes’ disease etiology
- Internship: Studying the role of peritoneal macrophages in endometriosis
- Internship: Measuring the anti-inflammatory and antitumour activity of dif- ferent drugs obtained by chemical synthesis
Teaching Experience
I am passionate about education. I have found teaching bioinformatics a joy
Introduction to Nextflow and longgwas tool
Virtual event
London, United Kingdom
2022
- Developed the content and the presentation
- Lectured a group of GP2 Trainees on Nextflow fundamentals, how to use the main Nextflow elements, and introduced longgwas tool
Bioinformatic analyses in Terra platform
Universidad Nacional Autónoma de México
Queretaro
2022
- Developed content and served as teaching assistant for this two day workshop
- We covered Terra platform basic concepts as well as hot to perform several analyses using GP2 data
- I tought on longitudinal GWAS and performing a cognitive decline PRS from GP2 Latino population data
Selected Publications
Genome-wide Analysis of Motor Progression in Parkinson Disease
Neurology Genetics
N/A
2023
- Alejandro Martínez-Carrasco, Raquel Real, Michael Lawton, Regina Hertfelder Reynolds, Manuela Tan, Lesley Wu, Nigel Williams, Camille Carroll, Jean-Christophe Corvol, Michele Hu, Donald Grosset, John Hardy, Mina Ryten, Yoav Ben-Shlomo, Maryam Shoai, Huw R Morris
- Role: First author
- DOI: https://doi.org/10.1212/NXG.0000000000200092
Genetic meta-analysis of levodopa induced dyskinesia in Parkinson’s disease
NPJ parkinson’s disease
N/A
2023
- Alejandro Martinez-Carrasco, Raquel Real, Michael Lawton, Hirotaka Iwaki, Manuela M. X. Tan, Lesley Wu, Nigel M. Williams, Camille Carroll, Michele T. M. Hu, Donald G. Grosset, John Hardy, Mina Ryten, Tom Foltynie, Yoav Ben-Shlomo, Maryam Shoai & Huw R. Morris
- Role: First author
- DOI: https://doi.org/10.1038/s41531-023-00573-2
Association between the LRP1B and APOE loci and the development of Parkinson’s disease dementiaris
Brain
N/A
2023
- Raquel Real, Alejandro Martinez-Carrasco, Regina H Reynolds, Michael A Lawton, Manuela MX Tan, Maryam Shoai, Jean-Christophe Corvol, Mina Ryten, Catherine Bresner, Leon Hubbard, Alexis Brice, Suzanne Lesage, Johann Faouzi, Alexis Elbaz, Fanny Artaud, Nigel Williams, Michele TM Hu, Yoav Ben-Shlomo, Donald G Grosset, John Hardy, Huw R Morris
- Role: Data analyst
- DOI: https://doi.org/10.1093/brain/awac414